African trypanosomiais, or sleeping sickness, is a parasitic disease transmitted by the tsetse fly. The disease is only found in the sub-Saharan countries in Africa, but it can affect millions. Currently an estimated 300,000 to 500,000 people are infected, and of those about 40,000 die each year. Symptoms of sleeping sickness begin with fever and headache and can continue to anemia, heart and kidney problems, and eventually can cause neurological damage. This damage can result in confusion, sleep cycle disruptions, lethargy, and insomnia. Without treatment, the disease is fatal.